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Correlation between polymorphisms of the NR3C1 gene and glucocorticoid effectiveness in patients with pemphigus vulgaris

Glucocorticoid (GC) resistance is the major obscule in the treatment of pemphigus vulgaris (PV) for both patients and clinicans with unclear mechanism. A hypotheis for this resistance is the mutations or polymorphisms present in the nuclear receptor subfamily 3, group C, member 1 (NR3C1) gene that e...

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Detalles Bibliográficos
Autores principales: Fang, Si-Yue, Li, Chun-Lei, Liu, Xiao-Song, Chen, Feng, Hua, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605666/
https://www.ncbi.nlm.nih.gov/pubmed/28928407
http://dx.doi.org/10.1038/s41598-017-12255-0