Ang-(1-7) is an endogenous β-arrestin-biased agonist of the AT(1) receptor with protective action in cardiac hypertrophy

The renin-angiotensin system (RAS) plays a key role in the control of vasoconstriction as well as sodium and fluid retention mediated mainly by angiotensin (Ang) II acting at the AT(1) receptor (AT1R). Ang-(1-7) is another RAS peptide, identified as the endogenous ligand of the Mas receptor and know...

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Detalles Bibliográficos
Autores principales: Teixeira, Larissa B., Parreiras-e-Silva, Lucas T., Bruder-Nascimento, Thiago, Duarte, Diego A., Simões, Sarah C., Costa, Rafael M., Rodríguez, Deisy Y., Ferreira, Pedro A. B., Silva, Carlos A. A., Abrao, Emiliana P., Oliveira, Eduardo B., Bouvier, Michel, Tostes, Rita C., Costa-Neto, Claudio M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605686/
https://www.ncbi.nlm.nih.gov/pubmed/28928410
http://dx.doi.org/10.1038/s41598-017-12074-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605686/
https://www.ncbi.nlm.nih.gov/pubmed/28928410
http://dx.doi.org/10.1038/s41598-017-12074-3

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