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Cross-talk between miR-471-5p and autophagy component proteins regulates LC3-associated phagocytosis (LAP) of apoptotic germ cells

Phagocytic clearance of apoptotic germ cells by Sertoli cells is vital for germ cell development and differentiation. Here, using a tissue-specific miRNA transgenic mouse model, we show that interaction between miR-471-5p and autophagy member proteins regulates clearance of apoptotic germ cells via...

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Detalles Bibliográficos
Autores principales: Panneerdoss, Subbarayalu, Viswanadhapalli, Suryavathi, Abdelfattah, Nourhan, Onyeagucha, Benjamin C., Timilsina, Santosh, Mohammad, Tabrez A., Chen, Yidong, Drake, Michael, Vuori, Kristiina, Kumar, T. Rajendra, Rao, Manjeet K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605700/
https://www.ncbi.nlm.nih.gov/pubmed/28928467
http://dx.doi.org/10.1038/s41467-017-00590-9