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Human stem cells alter the invasive properties of somatic cells via paracrine activation of mTORC1

Controlled invasion is essential during many physiological processes, whereas its deregulation is a hallmark of cancer. Here we demonstrate that embryonic, induced pluripotent and amniotic fluid stem cells share the property to induce the invasion of primary somatic cells of various origins through...

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Detalles Bibliográficos
Autores principales: Rosner, Margit, Pham, Ha Thi Thanh, Moriggl, Richard, Hengstschläger, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605703/
https://www.ncbi.nlm.nih.gov/pubmed/28928383
http://dx.doi.org/10.1038/s41467-017-00661-x