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Nrf2/HO-1 mediates the neuroprotective effect of mangiferin on early brain injury after subarachnoid hemorrhage by attenuating mitochondria-related apoptosis and neuroinflammation

Early brain injury (EBI) is involved in the process of cerebral tissue damage caused by subarachnoid hemorrhage (SAH), and multiple mechanisms, such as apoptosis and inflammation, participate in its development. Mangiferin (MF), a natural C-glucoside xanthone, has been reported to exert beneficial e...

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Detalles Bibliográficos
Autores principales: Wang, Zefeng, Guo, Songxue, Wang, Junxing, Shen, Yuanyuan, Zhang, Jianmin, Wu, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605716/
https://www.ncbi.nlm.nih.gov/pubmed/28928429
http://dx.doi.org/10.1038/s41598-017-12160-6