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Nrf2/HO-1 mediates the neuroprotective effect of mangiferin on early brain injury after subarachnoid hemorrhage by attenuating mitochondria-related apoptosis and neuroinflammation
Early brain injury (EBI) is involved in the process of cerebral tissue damage caused by subarachnoid hemorrhage (SAH), and multiple mechanisms, such as apoptosis and inflammation, participate in its development. Mangiferin (MF), a natural C-glucoside xanthone, has been reported to exert beneficial e...
Autores principales: | Wang, Zefeng, Guo, Songxue, Wang, Junxing, Shen, Yuanyuan, Zhang, Jianmin, Wu, Qun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605716/ https://www.ncbi.nlm.nih.gov/pubmed/28928429 http://dx.doi.org/10.1038/s41598-017-12160-6 |
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