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Transcribing β-cell mitochondria in health and disease
BACKGROUND: The recent genome-wide association studies (GWAS) of Type 2 Diabetes (T2D) have identified the pancreatic β-cell as the culprit in the pathogenesis of the disease. Mitochondrial metabolism plays a crucial role in the processes controlling release of insulin and β-cell mass. This notion i...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605719/ https://www.ncbi.nlm.nih.gov/pubmed/28951827 http://dx.doi.org/10.1016/j.molmet.2017.05.014 |