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Cyanobacterial Sfp-type phosphopantetheinyl transferases functionalize carrier proteins of diverse biosynthetic pathways

Cyanobacteria produce structurally and functionally diverse polyketides, nonribosomal peptides and their hybrids. Sfp-type phosphopantetheinyl transferases (PPTases) are essential to the production of these compounds via functionalizing carrier proteins (CPs) of biosynthetic megaenzymes. However, cy...

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Detalles Bibliográficos
Autores principales: Yang, Guang, Zhang, Yi, Lee, Nicholas K., Cozad, Monica A., Kearney, Sara E., Luesch, Hendrik, Ding, Yousong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605751/
https://www.ncbi.nlm.nih.gov/pubmed/28928426
http://dx.doi.org/10.1038/s41598-017-12244-3