Repurposing Lesogaberan to Promote Human Islet Cell Survival and β-Cell Replication

The activation of β-cell's A- and B-type gamma-aminobutyric acid receptors (GABA(A)-Rs and GABA(B)-Rs) can promote their survival and replication, and the activation of α-cell GABA(A)-Rs promotes their conversion into β-cells. However, GABA and the most clinically applicable GABA-R ligands may...

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Detalles Bibliográficos
Autores principales: Tian, Jide, Dang, Hoa, Hu, Angela, Xu, Willem, Kaufman, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605788/
https://www.ncbi.nlm.nih.gov/pubmed/29018828
http://dx.doi.org/10.1155/2017/6403539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605788/
https://www.ncbi.nlm.nih.gov/pubmed/29018828
http://dx.doi.org/10.1155/2017/6403539

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