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Repurposing Lesogaberan to Promote Human Islet Cell Survival and β-Cell Replication
The activation of β-cell's A- and B-type gamma-aminobutyric acid receptors (GABA(A)-Rs and GABA(B)-Rs) can promote their survival and replication, and the activation of α-cell GABA(A)-Rs promotes their conversion into β-cells. However, GABA and the most clinically applicable GABA-R ligands may...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605788/ https://www.ncbi.nlm.nih.gov/pubmed/29018828 http://dx.doi.org/10.1155/2017/6403539 |