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Toxicity evaluation of methoxy poly(ethylene oxide)-block-poly(ε-caprolactone) polymeric micelles following multiple oral and intraperitoneal administration to rats

Methoxy poly(ethylene oxide)-block-poly(ɛ-caprolactone) (PEO-b-PCL) copolymers are amphiphilic and biodegradable copolymers designed to deliver a variety of drugs and diagnostic agents. The aim of this study was to synthesize PEO-b-PCL block copolymers and assess the toxic effects of drug-free PEO-b...

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Detalles Bibliográficos
Autores principales: Binkhathlan, Ziyad, Qamar, Wajhul, Ali, Raisuddin, Kfoury, Hala, Alghonaim, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605849/
https://www.ncbi.nlm.nih.gov/pubmed/28951683
http://dx.doi.org/10.1016/j.jsps.2017.04.001