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Variation in Extracellular Detoxification Is a Link to Different Carcinogenicity among Chromates in Rodent and Human Lungs

[Image: see text] Inhalation of soluble chromium(VI) is firmly linked with higher risks of lung cancer in humans. However, comparative studies in rats have found a high lung tumorigenicity for moderately soluble chromates but no tumors for highly soluble chromates. These major species differences re...

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Detalles Bibliográficos
Autores principales: Krawic, Casey, Luczak, Michal W., Zhitkovich, Anatoly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605882/
https://www.ncbi.nlm.nih.gov/pubmed/28759204
http://dx.doi.org/10.1021/acs.chemrestox.7b00172