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Synthesis, molecular modeling and anticancer activity of new coumarin containing compounds

A series of new coumarin containing compounds were synthesized from 4-bromomethylcoumarin derivatives 2a, b and different heteroaromatic systems 4a-e, 6a-d, 8, 10via methylene thiolinker. Twenty-four compounds were screened biologically against two human tumor cell lines, breast carcinoma MCF-7 and...

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Detalles Bibliográficos
Autores principales: Morsy, Shaimaa A., Farahat, Abdelbasset A., Nasr, Magda N.A., Tantawy, Atif S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605891/
https://www.ncbi.nlm.nih.gov/pubmed/28951673
http://dx.doi.org/10.1016/j.jsps.2017.02.003