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Overexpression of interleukin-15 in mice promotes resistance to diet-induced obesity, increased insulin sensitivity, and markers of oxidative skeletal muscle metabolism

Interleukin-15 (IL-15) is a cytokine that is highly expressed in skeletal muscle. In addition to its well-characterized effects on innate immunity, IL-15 has been proposed to modulate skeletal muscle and adipose tissue mass, as well as insulin sensitivity. In the present study, an IL-15 gain-of-func...

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Detalles Bibliográficos
Autores principales: Quinn, LeBris S, Anderson, Barbara G, Conner, Jennifer D, Pistilli, Emidio E, Wolden-Hanson, Tami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605924/
https://www.ncbi.nlm.nih.gov/pubmed/28943758
http://dx.doi.org/10.2147/IJICMR.S19007