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Cell Cycle Inhibition To Treat Sleeping Sickness

African trypanosomiasis is caused by infection with the protozoan parasite Trypanosoma brucei. During infection, this pathogen divides rapidly to high density in the bloodstream of its mammalian host in a manner similar to that of leukemia. Like all eukaryotes, T. brucei has a cell cycle involving t...

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Detalles Bibliográficos
Autores principales: Epting, Conrad L., Emmer, Brian T., Du, Nga Y., Taylor, Joann M., Makanji, Ming Y., Olson, Cheryl L., Engman, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605941/
https://www.ncbi.nlm.nih.gov/pubmed/28928213
http://dx.doi.org/10.1128/mBio.01427-17