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Testing the excitation/inhibition imbalance hypothesis in a mouse model of the autism spectrum disorder: in vivo neurospectroscopy and molecular evidence for regional phenotypes

BACKGROUND: Excitation/inhibition (E/I) imbalance remains a widely discussed hypothesis in autism spectrum disorders (ASD). The presence of such an imbalance may potentially define a therapeutic target for the treatment of cognitive disabilities related to this pathology. Consequently, the study of...

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Detalles Bibliográficos
Autores principales: Gonçalves, Joana, Violante, Inês R., Sereno, José, Leitão, Ricardo A., Cai, Ying, Abrunhosa, Antero, Silva, Ana Paula, Silva, Alcino J., Castelo-Branco, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605987/
https://www.ncbi.nlm.nih.gov/pubmed/28932379
http://dx.doi.org/10.1186/s13229-017-0166-4