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Protecting effect of PrP codons M142 and K222 in goats orally challenged with bovine spongiform encephalopathy prions

Breeding towards genetic resistance to prion disease is effective in eliminating scrapie. In sheep, classical forms of scrapie have been eradicated almost completely in several countries by breeding programs using a prion protein (PrP) gene (PRNP) amino acid polymorphism. For goats, field and experi...

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Detalles Bibliográficos
Autores principales: Fast, C., Goldmann, W., Berthon, P., Tauscher, K., Andréoletti, O., Lantier, I., Rossignol, C., Bossers, A., Jacobs, J. G., Hunter, N., Groschup, M. H., Lantier, F., Langeveld, J. P. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606029/
https://www.ncbi.nlm.nih.gov/pubmed/28927447
http://dx.doi.org/10.1186/s13567-017-0455-0