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Tumor necrosis factor superfamily ligand mRNA expression profiles differ between humans and mice during homeostasis and between various murine kidney injuries

BACKGROUND: Several tumour necrosis factor (TNF) based therapeutics have already been approved for human use and several others are emerging. Therefore, we determined the mRNA expression levels of the TNF superfamily ligands (TNFSF) – e.g. TNF-α, lymphotoxin (LT)-α, LT-β, Fas-L (CD95-L), TNF-related...

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Detalles Bibliográficos
Autores principales: Devarapu, Satish Kumar, Grill, Julia Felicitas, Xie, Junhui, Weidenbusch, Marc, Honarpisheh, Mohsen, Vielhauer, Volker, Anders, Hans-Joachim, Mulay, Shrikant R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606058/
https://www.ncbi.nlm.nih.gov/pubmed/28927419
http://dx.doi.org/10.1186/s12929-017-0383-3