SiFit: inferring tumor trees from single-cell sequencing data under finite-sites models

Single-cell sequencing enables the inference of tumor phylogenies that provide insights on intra-tumor heterogeneity and evolutionary trajectories. Recently introduced methods perform this task under the infinite-sites assumption, violations of which, due to chromosomal deletions and loss of heteroz...

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Detalles Bibliográficos
Autores principales: Zafar, Hamim, Tzen, Anthony, Navin, Nicholas, Chen, Ken, Nakhleh, Luay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606061/
https://www.ncbi.nlm.nih.gov/pubmed/28927434
http://dx.doi.org/10.1186/s13059-017-1311-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606061/
https://www.ncbi.nlm.nih.gov/pubmed/28927434
http://dx.doi.org/10.1186/s13059-017-1311-2

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