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db/db Mice Exhibit Features of Human Type 2 Diabetes That Are Not Present in Weight-Matched C57BL/6J Mice Fed a Western Diet

To understand features of human obesity and type 2 diabetes mellitus (T2D) that can be recapitulated in the mouse, we compared C57BL/6J mice fed a Western-style diet (WD) to weight-matched genetically obese leptin receptor-deficient mice (db/db). All mice were monitored for changes in body compositi...

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Detalles Bibliográficos
Autores principales: Burke, Susan J., Batdorf, Heidi M., Burk, David H., Noland, Robert C., Eder, Adrianna E., Boulos, Matthew S., Karlstad, Michael D., Collier, J. Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606106/
https://www.ncbi.nlm.nih.gov/pubmed/29038790
http://dx.doi.org/10.1155/2017/8503754