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A systematic review and integrative approach to decode the common molecular link between levodopa response and Parkinson’s disease

BACKGROUND: PD is a progressive neurodegenerative disorder commonly treated by levodopa. The findings from genetic studies on adverse effects (ADRs) and levodopa efficacy are mostly inconclusive. Here, we aim to identify predictive genetic biomarkers for levodopa response (LR) and determine common m...

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Detalles Bibliográficos
Autores principales: Guin, Debleena, Mishra, Manish Kumar, Talwar, Puneet, Rawat, Chitra, Kushwaha, Suman S., Kukreti, Shrikant, Kukreti, Ritushree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606117/
https://www.ncbi.nlm.nih.gov/pubmed/28927418
http://dx.doi.org/10.1186/s12920-017-0291-0