Crystal structure of the UBR‐box from UBR6/FBXO11 reveals domain swapping mediated by zinc binding

The UBR‐box is a 70‐residue zinc finger domain present in the UBR family of E3 ubiquitin ligases that directly binds N‐terminal degradation signals in substrate proteins. UBR6, also called FBXO11, is an UBR‐box containing E3 ubiquitin ligase that does not bind N‐terminal signals. Here, we present th...

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Detalles Bibliográficos
Autores principales: Muñoz‐Escobar, Juliana, Kozlov, Guennadi, Gehring, Kalle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Protein Structure Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606531/
https://www.ncbi.nlm.nih.gov/pubmed/28691247
http://dx.doi.org/10.1002/pro.3227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606531/
https://www.ncbi.nlm.nih.gov/pubmed/28691247
http://dx.doi.org/10.1002/pro.3227

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