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Analysis of sequence data to identify potential risk variants for oral clefts in multiplex families

BACKGROUND: Nonsyndromic oral clefts are craniofacial malformations, which include cleft lip with or without cleft palate. The etiology for oral clefts is complex with both genetic and environmental factors contributing to risk. Previous genome‐wide association (GWAS) studies have identified multipl...

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Detalles Bibliográficos
Autores principales: Holzinger, Emily R., Li, Qing, Parker, Margaret M., Hetmanski, Jacqueline B., Marazita, Mary L., Mangold, Elisabeth, Ludwig, Kerstin U., Taub, Margaret A., Begum, Ferdouse, Murray, Jeffrey C., Albacha‐Hejazi, Hasan, Alqosayer, Khalid, Al‐Souki, Giath, Albasha Hejazi, Abdullatiff, Scott, Alan F., Beaty, Terri H., Bailey‐Wilson, Joan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606860/
https://www.ncbi.nlm.nih.gov/pubmed/28944239
http://dx.doi.org/10.1002/mgg3.320