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NDFIP allows NEDD4/NEDD4L-induced AQP2 ubiquitination and degradation

Regulation of our water homeostasis is fine-tuned by dynamic translocation of Aquaporin-2 (AQP2)-bearing vesicles to and from the plasma membrane of renal principal cells. Whereas binding of vasopressin to its type-2 receptor initiates a cAMP-protein kinase A cascade and AQP2 translocation to the ap...

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Detalles Bibliográficos
Autores principales: Trimpert, Christiane, Wesche, Daniel, de Groot, Theun, Pimentel Rodriguez, Martha M., Wong, Victoria, van den Berg, Dennis T. M., Cheval, Lydie, Ariza, Carolina A., Doucet, Alain, Stagljar, Igor, Deen, Peter M. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606929/
https://www.ncbi.nlm.nih.gov/pubmed/28931009
http://dx.doi.org/10.1371/journal.pone.0183774