TGFβR signalling controls CD103(+)CD11b(+) dendritic cell development in the intestine

CD103(+)CD11b(+) dendritic cells (DCs) are unique to the intestine, but the factors governing their differentiation are unclear. Here we show that transforming growth factor receptor 1 (TGFβR1) has an indispensable, cell intrinsic role in the development of these cells. Deletion of Tgfbr1 results in...

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Detalles Bibliográficos
Autores principales: Bain, C. C., Montgomery, J., Scott, C. L., Kel, J. M., Girard-Madoux, M. J. H., Martens, L., Zangerle-Murray, T. F. P., Ober-Blöbaum, J., Lindenbergh-Kortleve, D., Samsom, J. N., Henri, S., Lawrence, T., Saeys, Y., Malissen, B., Dalod, M., Clausen, B. E., Mowat, A. McI.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607002/
https://www.ncbi.nlm.nih.gov/pubmed/28931816
http://dx.doi.org/10.1038/s41467-017-00658-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607002/
https://www.ncbi.nlm.nih.gov/pubmed/28931816
http://dx.doi.org/10.1038/s41467-017-00658-6

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