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Excitability is increased in hippocampal CA1 pyramidal cells of Fmr1 knockout mice

Fragile X syndrome (FXS) is caused by a failure of neuronal cells to express the gene encoding the fragile mental retardation protein (FMRP). Clinical features of the syndrome include intellectual disability, learning impairment, hyperactivity, seizures and anxiety. Fmr1 knockout (KO) mice do not ex...

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Detalles Bibliográficos
Autores principales: Luque, M. Angeles, Beltran-Matas, Pablo, Marin, M. Carmen, Torres, Blas, Herrero, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607184/
https://www.ncbi.nlm.nih.gov/pubmed/28931075
http://dx.doi.org/10.1371/journal.pone.0185067