rahu is a mutant allele of Dnmt3c, encoding a DNA methyltransferase homolog required for meiosis and transposon repression in the mouse male germline

Transcriptional silencing by heritable cytosine-5 methylation is an ancient strategy to repress transposable elements. It was previously thought that mammals possess four DNA methyltransferase paralogs—Dnmt1, Dnmt3a, Dnmt3b and Dnmt3l—that establish and maintain cytosine-5 methylation. Here we ident...

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Detalles Bibliográficos
Autores principales: Jain, Devanshi, Meydan, Cem, Lange, Julian, Claeys Bouuaert, Corentin, Lailler, Nathalie, Mason, Christopher E., Anderson, Kathryn V., Keeney, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607212/
https://www.ncbi.nlm.nih.gov/pubmed/28854222
http://dx.doi.org/10.1371/journal.pgen.1006964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607212/
https://www.ncbi.nlm.nih.gov/pubmed/28854222
http://dx.doi.org/10.1371/journal.pgen.1006964

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