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Organ-specific regulation of ATP7A abundance is coordinated with systemic copper homeostasis
Copper (Cu) is an essential cofactor for various enzymatic activities including mitochondrial electron transport, iron mobilization, and peptide hormone maturation. Consequently, Cu dysregulation is associated with fatal neonatal disease, liver and cardiac dysfunction, and anemia. While the Cu trans...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607234/ https://www.ncbi.nlm.nih.gov/pubmed/28931909 http://dx.doi.org/10.1038/s41598-017-11961-z |