Chimeric 14-3-3 proteins for unraveling interactions with intrinsically disordered partners

In eukaryotes, several “hub” proteins integrate signals from different interacting partners that bind through intrinsically disordered regions. The 14-3-3 protein hub, which plays wide-ranging roles in cellular processes, has been linked to numerous human disorders and is a promising target for ther...

Descripción completa

Detalles Bibliográficos
Autores principales: Sluchanko, Nikolai N., Tugaeva, Kristina V., Greive, Sandra J., Antson, Alfred A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607241/
https://www.ncbi.nlm.nih.gov/pubmed/28931924
http://dx.doi.org/10.1038/s41598-017-12214-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607241/
https://www.ncbi.nlm.nih.gov/pubmed/28931924
http://dx.doi.org/10.1038/s41598-017-12214-9

Ejemplares similares