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Abnormal arterial-venous fusions and fate specification in mouse embryos lacking blood flow

The functions of blood flow in the morphogenesis of mammalian arteries and veins are not well understood. We examined the development of the dorsal aorta (DA) and the cardinal vein (CV) in Ncx1 (−/−) mutants, which lack blood flow due to a deficiency in a sodium calcium ion exchanger expressed speci...

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Detalles Bibliográficos
Autores principales: Hwa, Jennifer J., Beckouche, Nathan, Huang, Lawrence, Kram, Yoseph, Lindskog, Henrik, Wang, Rong A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607254/
https://www.ncbi.nlm.nih.gov/pubmed/28931948
http://dx.doi.org/10.1038/s41598-017-12353-z