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Circulating Mycobacterium tuberculosis DosR latency antigen-specific, polyfunctional, regulatory IL10(+) Th17 CD4 T-cells differentiate latent from active tuberculosis

The functional heterogeneity of T cell responses to diverse antigens expressed at different stages of Mycobacterium tuberculosis (Mtb) infection, in particular early secreted versus dormancy related latency antigens expressed later, that distinguish subjects with latent (LTBI), pulmonary (PTB) or ex...

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Detalles Bibliográficos
Autores principales: Rakshit, Srabanti, Adiga, Vasista, Nayak, Soumya, Sahoo, Pravat Nalini, Sharma, Prabhat Kumar, van Meijgaarden, Krista E., UK J., Anto Jesuraj, Dhar, Chirag, Souza, George D., Finak, Greg, De Rosa, Stephen C., Ottenhoff, Tom H. M., Vyakarnam, Annapurna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607261/
https://www.ncbi.nlm.nih.gov/pubmed/28931830
http://dx.doi.org/10.1038/s41598-017-10773-5