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Hyperhomocysteinemia Alters Retinal Endothelial Cells Barrier Function and Angiogenic Potential via Activation of Oxidative Stress

Hyperhomocysteinemia (HHcy) is associated with several human visual disorders, such as diabetic retinopathy (DR) and age-related macular degeneration (AMD). Breakdown of the blood-retinal barrier (BRB) is linked to vision loss in DR and AMD. Our previous work revealed that HHcy altered BRB in retina...

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Detalles Bibliográficos
Autores principales: Mohamed, Riyaz, Sharma, Isha, Ibrahim, Ahmed S., Saleh, Heba, Elsherbiny, Nehal M., Fulzele, Sadanand, Elmasry, Khaled, Smith, Sylvia B., Al-Shabrawey, Mohamed, Tawfik, Amany
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607263/
https://www.ncbi.nlm.nih.gov/pubmed/28931831
http://dx.doi.org/10.1038/s41598-017-09731-y