Salidroside ameliorates sepsis-induced acute lung injury and mortality via downregulating NF-κB and HMGB1 pathways through the upregulation of SIRT1

Sepsis is a life-threatening medical condition. Salidroside, a substance isolated from Rhodiola rosea, possesses antioxidant and anti-inflammatory properties. The effect and mechanism of salidroside on sepsis-induced acute lung injury still remains to be well clarified. Here, we investigated the eff...

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Detalles Bibliográficos
Autores principales: Lan, Kuo-Cheng, Chao, Sung-Chuan, Wu, Hsiao-Yi, Chiang, Chia-Lien, Wang, Ching-Chia, Liu, Shing-Hwa, Weng, Te-I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607272/
https://www.ncbi.nlm.nih.gov/pubmed/28931916
http://dx.doi.org/10.1038/s41598-017-12285-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607272/
https://www.ncbi.nlm.nih.gov/pubmed/28931916
http://dx.doi.org/10.1038/s41598-017-12285-8

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