Cargando…

Salidroside ameliorates sepsis-induced acute lung injury and mortality via downregulating NF-κB and HMGB1 pathways through the upregulation of SIRT1

Sepsis is a life-threatening medical condition. Salidroside, a substance isolated from Rhodiola rosea, possesses antioxidant and anti-inflammatory properties. The effect and mechanism of salidroside on sepsis-induced acute lung injury still remains to be well clarified. Here, we investigated the eff...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lan, Kuo-Cheng, Chao, Sung-Chuan, Wu, Hsiao-Yi, Chiang, Chia-Lien, Wang, Ching-Chia, Liu, Shing-Hwa, Weng, Te-I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607272/ https://www.ncbi.nlm.nih.gov/pubmed/28931916 http://dx.doi.org/10.1038/s41598-017-12285-8

Ejemplares similares

Salidroside Inhibits HMGB1 Acetylation and Release through Upregulation of SirT1 during Inflammation
por: Qi, Zhilin, et al.
Publicado: (2017)

Salidroside Ameliorates Ultraviolet-Induced Keratinocyte Injury by Inducing SIRT1-Dependent Autophagy
por: Ke, Jin, et al.
Publicado: (2022)

Salidroside Ameliorates Cardiomyocyte Hypertrophy by Upregulating Peroxisome Proliferator-Activated Receptor-α
por: Gao, Hui, et al.
Publicado: (2022)

The SIRT1-HMGB1 axis: Therapeutic potential to ameliorate inflammatory responses and tumor occurrence
por: Wei, Lanyi, et al.
Publicado: (2022)

Xuebijing Ameliorates Sepsis-Induced Lung Injury by Downregulating HMGB1 and RAGE Expressions in Mice
por: Wang, Qiao, et al.
Publicado: (2015)

Estrogen modulates vascular smooth muscle cell function through downregulation of SIRT1
por: Lee, Chien-Hsing, et al.
Publicado: (2017)

Salidroside inhibits MAPK, NF-κB, and STAT3 pathways in psoriasis-associated oxidative stress via SIRT1 activation
por: Xu, Fengli, et al.
Publicado: (2019)

Matrine Ameliorates Colorectal Cancer in Rats via Inhibition of HMGB1 Signaling and Downregulation of IL-6, TNF-α, and HMGB1
por: Fan, Huizhen, et al.
Publicado: (2018)

Diacerein ameliorates acetaminophen hepatotoxicity in rats via inhibiting HMGB1/TLR4/NF-κB and upregulating PPAR-γ signal
por: Mohamed Kamel, Gellan Alaa, et al.
Publicado: (2022)

Baicalin Ameliorates Cognitive Impairment and Protects Microglia from LPS-Induced Neuroinflammation via the SIRT1/HMGB1 Pathway
por: Li, Yue, et al.
Publicado: (2020)

Salidroside Ameliorates Renal Interstitial Fibrosis by Inhibiting the TLR4/NF-κB and MAPK Signaling Pathways
por: Li, Rui, et al.
Publicado: (2019)

Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways
por: Feng, Jiao, et al.
Publicado: (2018)

Salidroside ameliorated hypoxia‐induced tumorigenesis of BxPC‐3 cells via downregulating hypoxia‐inducible factor (HIF)‐1α and LOXL2
por: Chen, Xiaoping, et al.
Publicado: (2019)

A Novel Resveratrol Analog Upregulates SIRT1 Expression and Ameliorates Neointima Formation
por: Yuan, Baohui, et al.
Publicado: (2021)

Chrysophanol alleviates myocardial injury in diabetic db/db mice by regulating the SIRT1/HMGB1/NF-κB signaling pathway
por: Xue, Peng, et al.
Publicado: (2019)

Vestibular rehabilitation ameliorates chronic dizziness through the SIRT1 axis
por: Kao, Chung-Lan, et al.
Publicado: (2014)

Corrigendum: A novel resveratrol analog upregulates SIRT1 expression and ameliorates neointima formation
por: Yuan, Baohui, et al.
Publicado: (2022)

Salidroside protects against ox-LDL-induced endothelial injury by enhancing autophagy mediated by SIRT1-FoxO1 pathway
por: Zhu, Zhongsheng, et al.
Publicado: (2019)

Salidroside ameliorates Adriamycin nephropathy in mice by inhibiting β‐catenin activity
por: Huang, Xinzhong, et al.
Publicado: (2019)

Salidroside ameliorates Parkinson's disease by inhibiting NLRP3-dependent pyroptosis
por: Zhang, Xue, et al.
Publicado: (2020)

Downregulation of HMGB1 in thymoma cells affects T cell differentiation
por: Li, Jian, et al.
Publicado: (2023)

Berberine Ameliorates Subarachnoid Hemorrhage Injury via Induction of Sirtuin 1 and Inhibiting HMGB1/Nf-κB Pathway
por: Zhang, Xiang-Hua, et al.
Publicado: (2020)

Downregulation of Sirt1 as aging change in advanced heart failure
por: Lu, Tse-Min, et al.
Publicado: (2014)

Kaempferol Improves Lung Ischemia-Reperfusion Injury via Antiinflammation and Antioxidative Stress Regulated by SIRT1/HMGB1/NF-κB Axis
por: Yang, Chunli, et al.
Publicado: (2020)

Salidroside reduces neuropathology in Alzheimer’s disease models by targeting NRF2/SIRT3 pathway
por: Yao, Yuyuan, et al.
Publicado: (2022)

Salidroside attenuates oxidized low-density lipoprotein-induced endothelial cell injury via promotion of the AMPK/SIRT1 pathway
por: Zhao, Dongming, et al.
Publicado: (2019)

Salidroside Delays Cellular Senescence by Stimulating Mitochondrial Biogenesis Partly through a miR-22/SIRT-1 Pathway
por: Mao, Gen-Xiang, et al.
Publicado: (2019)

Tubeimoside I Ameliorates Doxorubicin-Induced Cardiotoxicity by Upregulating SIRT3
por: Zhang, Wei, et al.
Publicado: (2023)

SIRT1-dependent mechanisms and effects of resveratrol for amelioration of muscle wasting in NASH mice
por: Liu, Chih-Wei, et al.
Publicado: (2020)

Magnesium sulfate ameliorates sepsis-induced diaphragm dysfunction in rats via inhibiting HMGB1/TLR4/NF-κB pathway
por: Jiang, Jihong, et al.
Publicado: (2020)

SIRT1 is downregulated by autophagy in senescence and aging
por: Xu, Caiyue, et al.
Publicado: (2020)

Blood purification treatment initiated at the time of sepsis diagnosis effectively attenuates serum HMGB1 upregulation and improves patient prognosis
por: Zheng, Shixiang, et al.
Publicado: (2017)

Astaxanthin Ameliorates high-fat diet-induced cardiac damage and fibrosis by upregulating and activating SIRT1
por: Shatoor, Abdullah S., et al.
Publicado: (2021)

Baiying qingmai formulation ameliorates thromboangiitis obliterans by inhibiting HMGB1/RAGE/NF-κB signaling pathways
por: Zou, Chongchong, et al.
Publicado: (2022)

Soluble CD93 lectin-like domain sequesters HMGB1 to ameliorate inflammatory diseases
por: Huang, Shang-En, et al.
Publicado: (2023)

Maslinic Acid Ameliorates Inflammation via the Downregulation of NF-κB and STAT-1
por: Lee, Wonhwa, et al.
Publicado: (2020)

Salidroside Ameliorates Alzheimer's Disease by Targeting NLRP3 Inflammasome-Mediated Pyroptosis
por: Cai, Yawen, et al.
Publicado: (2022)

Salidroside Ameliorates Radiation Damage by Reducing Mitochondrial Oxidative Stress in the Submandibular Gland
por: Sun, Yue-Mei, et al.
Publicado: (2022)

Relevance of SIRT1-NF-κB Axis as Therapeutic Target to Ameliorate Inflammation in Liver Disease
por: de Gregorio, Estefanía, et al.
Publicado: (2020)

HMGB1 promotes HCC progression partly by downregulating p21 via ERK/c-Myc pathway and upregulating MMP-2
por: Chen, Yanmei, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_b9n8vvj0gro0rgblv595fme86o