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Loss of p73 in ependymal cells during the perinatal period leads to aqueductal stenosis
The p53 family member p73 plays a critical role in brain development. p73 knockout mice exhibit a number of deficits in the nervous system, such as neuronal death, hydrocephalus, hippocampal dysgenesis, and pheromonal defects. Among these phenotypes, the mechanisms of hydrocephalus remain unknown. I...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607290/ https://www.ncbi.nlm.nih.gov/pubmed/28931858 http://dx.doi.org/10.1038/s41598-017-12105-z |