High-throughput targeted screening in triple-negative breast cancer cells identifies Wnt-inhibiting activities in Pacific brittle stars

Pro-proliferative oncogenic signaling is one of the hallmarks of cancer. Specific targeting of such signaling pathways is one of the main approaches to modern anti-cancer drug discovery, as opposed to more traditional search for general cytotoxic agents. Natural products, especially from marine sour...

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Detalles Bibliográficos
Autores principales: Blagodatski, Artem, Cherepanov, Vsevolod, Koval, Alexey, Kharlamenko, Vladimir I., Khotimchenko, Yuri S., Katanaev, Vladimir L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607299/
https://www.ncbi.nlm.nih.gov/pubmed/28931883
http://dx.doi.org/10.1038/s41598-017-12232-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607299/
https://www.ncbi.nlm.nih.gov/pubmed/28931883
http://dx.doi.org/10.1038/s41598-017-12232-7

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