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A Novel H2S-releasing Amino-Bisphosphonate which combines bone anti-catabolic and anabolic functions
Bisphosphonates (BPs) are the first-line treatment of bone loss resulting from various pathological conditions. Due to their high affinity to bone they have been used to develop conjugates with pro-anabolic or anti-catabolic drugs. We recently demontrated that hydrogen sulfide (H(2)S), promotes oste...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607332/ https://www.ncbi.nlm.nih.gov/pubmed/28931828 http://dx.doi.org/10.1038/s41598-017-11608-z |