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Altered methylations of H19, Snrpn, Mest and Peg3 are reversible by developmental reprogramming in kidney tissue of ICSI-derived mice

Although the prevalence of Intracytoplasmic sperm injection (ICSI) has increased year by year, there remains concern about the safety of these procedures because of reports of the increased risk for imprinting disorders. Previous research has demonstrated that gonadotropin stimulation contributes to...

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Detalles Bibliográficos
Autores principales: Zhan, Qitao, Qi, Xuchen, Wang, Ning, Le, Fang, Mao, Luna, Yang, Xinyun, Yuan, Mu, Lou, Hangying, Xu, Xiangrong, Chen, Xijing, Jin, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607335/
https://www.ncbi.nlm.nih.gov/pubmed/28931827
http://dx.doi.org/10.1038/s41598-017-11778-w