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Identification and correction of spatial bias are essential for obtaining quality data in high-throughput screening technologies

Spatial bias continues to be a major challenge in high-throughput screening technologies. Its successful detection and elimination are critical for identifying the most promising drug candidates. Here, we examine experimental small molecule assays from the popular ChemBank database and show that scr...

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Detalles Bibliográficos
Autores principales: Mazoure, Bogdan, Nadon, Robert, Makarenkov, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607347/
https://www.ncbi.nlm.nih.gov/pubmed/28931934
http://dx.doi.org/10.1038/s41598-017-11940-4