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Identification and correction of spatial bias are essential for obtaining quality data in high-throughput screening technologies
Spatial bias continues to be a major challenge in high-throughput screening technologies. Its successful detection and elimination are critical for identifying the most promising drug candidates. Here, we examine experimental small molecule assays from the popular ChemBank database and show that scr...
Autores principales: | Mazoure, Bogdan, Nadon, Robert, Makarenkov, Vladimir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607347/ https://www.ncbi.nlm.nih.gov/pubmed/28931934 http://dx.doi.org/10.1038/s41598-017-11940-4 |
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