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Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6
The diversity of mesenchymal cell types in the lung that influence epithelial homeostasis and regeneration is poorly defined. We used genetic lineage tracing, single-cell RNA sequencing, and organoid culture approaches to show that Lgr5 and Lgr6, well-known markers of stem cells in epithelial tissue...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607351/ https://www.ncbi.nlm.nih.gov/pubmed/28886383 http://dx.doi.org/10.1016/j.cell.2017.07.028 |