Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6

The diversity of mesenchymal cell types in the lung that influence epithelial homeostasis and regeneration is poorly defined. We used genetic lineage tracing, single-cell RNA sequencing, and organoid culture approaches to show that Lgr5 and Lgr6, well-known markers of stem cells in epithelial tissue...

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Detalles Bibliográficos
Autores principales: Lee, Joo-Hyeon, Tammela, Tuomas, Hofree, Matan, Choi, Jinwook, Marjanovic, Nemanja Despot, Han, Seungmin, Canner, David, Wu, Katherine, Paschini, Margherita, Bhang, Dong Ha, Jacks, Tyler, Regev, Aviv, Kim, Carla F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607351/
https://www.ncbi.nlm.nih.gov/pubmed/28886383
http://dx.doi.org/10.1016/j.cell.2017.07.028

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