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Genetic Evidence for Erythrocyte Receptor Glycophorin B Expression Levels Defining a Dominant Plasmodium falciparum Invasion Pathway into Human Erythrocytes

Plasmodium falciparum, the parasite that causes the deadliest form of malaria, has evolved multiple proteins known as invasion ligands that bind to specific erythrocyte receptors to facilitate invasion of human erythrocytes. The EBA-175/glycophorin A (GPA) and Rh5/basigin ligand-receptor interaction...

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Detalles Bibliográficos
Autores principales: Dankwa, Selasi, Chaand, Mudit, Kanjee, Usheer, Jiang, Rays H. Y., Nobre, Luis V., Goldberg, Jonathan M., Bei, Amy K., Moechtar, Mischka A., Grüring, Christof, Ahouidi, Ambroise D., Ndiaye, Daouda, Dieye, Tandakha N., Mboup, Souleymane, Weekes, Michael P., Duraisingh, Manoj T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607420/
https://www.ncbi.nlm.nih.gov/pubmed/28760933
http://dx.doi.org/10.1128/IAI.00074-17