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Topological organization and dynamic regulation of human tRNA genes during macrophage differentiation
BACKGROUND: The human genome is hierarchically organized into local and long-range structures that help shape cell-type-specific transcription patterns. Transfer RNA (tRNA) genes (tDNAs), which are transcribed by RNA polymerase III (RNAPIII) and encode RNA molecules responsible for translation, are...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607496/ https://www.ncbi.nlm.nih.gov/pubmed/28931413 http://dx.doi.org/10.1186/s13059-017-1310-3 |