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Cell type-specific effects of p27(KIP1) loss on retinal development

BACKGROUND: Cyclin-dependent kinase (CDK) inhibitors play an important role in regulating cell cycle progression, cell cycle exit and cell differentiation. p27(KIP1) (p27), one of the major CDK inhibitors in the retina, has been shown to control the timing of cell cycle exit of retinal progenitors....

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Detalles Bibliográficos
Autores principales: Ogawa, Mariko, Saitoh, Fuminori, Sudou, Norihiro, Sato, Fumi, Fujieda, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607500/
https://www.ncbi.nlm.nih.gov/pubmed/28931408
http://dx.doi.org/10.1186/s13064-017-0094-1