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Genetic alterations of IDH1 and Vegf in brain tumors

BACKGROUND: This study evaluates the presence of R132H mutation in isocitrate dehydrogenase (IDH1) gene and the vascular endothelial growth factor (VEGF) +936 C/T polymorphism in brain tumors. The impact of these genetic alterations on overall survival (OS) and progression free survival (PFS) was ev...

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Detalles Bibliográficos
Autores principales: Veganzones, Silvia, de la Orden, Virginia, Requejo, Lucía, Mediero, Beatriz, González, María Luisa, del Prado, Náyade, Rodríguez García, Carmen, Gutiérrez‐González, Raquel, Pérez‐Zamarrón, Alvaro, Martínez, Armando, Maestro, Marisa L., Zimman, Horacio Mario, González‐Neira, Anna, Vaquero, Jesús, Rodríguez‐Boto, Gregorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607534/
https://www.ncbi.nlm.nih.gov/pubmed/28948065
http://dx.doi.org/10.1002/brb3.718