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Linking kindling to increased glutamate release in the dentate gyrus of the hippocampus through the STXBP5/tomosyn‐1 gene

INTRODUCTION: In kindling, repeated electrical stimulation of certain brain areas causes progressive and permanent intensification of epileptiform activity resulting in generalized seizures. We focused on the role(s) of glutamate and a negative regulator of glutamate release, STXBP5/tomosyn‐1, in ki...

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Detalles Bibliográficos
Autores principales: Batten, Seth R., Matveeva, Elena A., Whiteheart, Sidney W., Vanaman, Thomas C., Gerhardt, Greg A., Slevin, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607557/
https://www.ncbi.nlm.nih.gov/pubmed/28948088
http://dx.doi.org/10.1002/brb3.795