Tracking progressive pathological and functional decline in the rTg4510 mouse model of tauopathy

BACKGROUND: The choice and appropriate use of animal models in drug discovery for Alzheimer’s disease (AD) is pivotal to successful clinical translation of novel therapeutics, yet true alignment of research is challenging. Current models do not fully recapitulate the human disease, and even exhibit...

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Detalles Bibliográficos
Autores principales: Blackmore, Thomas, Meftah, Soraya, Murray, Tracey Karen, Craig, Peter James, Blockeel, Anthony, Phillips, Keith, Eastwood, Brian, O’Neill, Michael J., Marston, Hugh, Ahmed, Zeshan, Gilmour, Gary, Gastambide, Francois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607580/
https://www.ncbi.nlm.nih.gov/pubmed/28931441
http://dx.doi.org/10.1186/s13195-017-0306-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607580/
https://www.ncbi.nlm.nih.gov/pubmed/28931441
http://dx.doi.org/10.1186/s13195-017-0306-2

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