Cargando…
VISMapper: ultra-fast exhaustive cartography of viral insertion sites for gene therapy
BACKGROUND: The possibility of integrating viral vectors to become a persistent part of the host genome makes them a crucial element of clinical gene therapy. However, viral integration has associated risks, such as the unintentional activation of oncogenes that can result in cancer. Therefore, the...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607581/ https://www.ncbi.nlm.nih.gov/pubmed/28931371 http://dx.doi.org/10.1186/s12859-017-1837-z |