Serotonin 5-HT6 receptors affect cognition in a mouse model of Alzheimer’s disease by regulating cilia function

BACKGROUND: Serotonin receptor 5-HT6 is involved in cognition and Alzheimer’s disease (AD) development. However, the mechanism of 5-HT6 in AD pathology is not clear. METHODS: Since 5-HT6 is almost exclusively expressed in the primary cilia, using immunostaining we examined the number of cilia in the...

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Detalles Bibliográficos
Autores principales: Hu, Lili, Wang, Bingjie, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607612/
https://www.ncbi.nlm.nih.gov/pubmed/28931427
http://dx.doi.org/10.1186/s13195-017-0304-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607612/
https://www.ncbi.nlm.nih.gov/pubmed/28931427
http://dx.doi.org/10.1186/s13195-017-0304-4

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